Press Releases
Looking for more press releases? Explore our full press release archive by date to access past announcements, news updates, and media releases published on Fiji Tech Network.
ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway
Life Science Alliance - New York
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May 23, 2024
Introduction The ER is the largest membrane-bound organelle and is involved in essential functions, including protein and lipid biosynthesis and calcium homeostasis. Similar to other cellular membranes, the ER lipid bilayer is organized in protein...
Distinct calcium sources regulate temporal profiles of NMDAR and mGluR-mediated protein synthesis
Life Science Alliance - New York
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May 15, 2024
Introduction Calcium, an important secondary messenger, lies at the hub of multiple signaling pathways (1). The increase in cytosolic calcium contributed by different calcium-permeable channels can create transient high-calcium microenvironments...
Transcript of Minister for Foreign Affairs Dr Vivian Balakrishnan's Joint Press Remarks with US Secretary of State Antony Blinken, 31 July 2024
Singapore Ministry of Foreign Affairs
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July 31, 2024
Minister Dr Vivian Balakrishnan: Good afternoon, everyone, and a very warm welcome to Singapore. Thank you to my good friend Tony. We live in an age of extraordinary opportunities and challenges. Technological developments have raced ahead at a...
Chemokine receptor hetero-oligomers regulate monocyte chemotaxis
Life Science Alliance - New York
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May 23, 2024
Introduction The super-family of seven-transmembrane (7TM) receptors, of which most are G protein–coupled receptors (GPCRs), are critical mediators of numerous physiological and pathological processes in the human body. Accordingly, GPCRs are the...
Defects in integrin complex formation promote CHKB-mediated muscular dystrophy
Life Science Alliance - New York
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May 15, 2024
Introduction The specialized plasma membrane of skeletal muscle, called sarcolemma, transmits force and is subjected to substantial stress during muscle contraction (1). To transmit and withstand force, the sarcolemma is firmly attached to the ECM...
Systems genetics analysis of human body fat distribution genes identifies adipocyte processes
Life Science Alliance - New York
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May 3, 2024
Introduction Obesity (measured as body mass index [BMI]) is a condition that affects roughly 40% of Americans (Hales et al, 2020) and significantly increases the risk of cardio-metabolic disease (Riaz et al, 2018; Cheng et al, 2019). Excess energy...
The F-actin bundler SWAP-70 promotes tumor metastasis
Life Science Alliance - New York
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May 17, 2024
Introduction By far, the largest fraction of cancer-related deaths occurs through metastasis, and thus, metastasis is the greatest challenge to cancer therapy. Although new approaches have been established, such as immune checkpoint or cell-based...
Glycolic acid and D-lactate--putative products of DJ-1--restore neurodegeneration in FUS - and SOD1-ALS
Life Science Alliance - New York
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May 17, 2024
Introduction Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease, with an estimate of 17,000 patients and ∼5,000 new cases annually only in Europe (Marin et al, 2017). Worldwide incidence is ∼1.6 cases per 100,000 persons...
The concerted action of SEPT9 and EPLIN modulates the adhesion and migration of human fibroblasts
Life Science Alliance - New York
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May 7, 2024
Introduction Septins were discovered in the budding yeast in the 1970s and were subsequently found to form a novel cytoskeletal system (Longtine et al, 1996). Unlike actin filaments and microtubules, septins assemble into non-polar filaments. The...
GDF15 controls primary cilia morphology and function thereby affecting progenitor proliferation
Life Science Alliance - New York
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May 7, 2024
Introduction Growth and differentiation factor 15 (GDF15), a divergent member of the TGF-β superfamily, regulates body weight by controlling food uptake via its receptor GDNF family receptor alpha-like (GFRAL). The latter is sparsely expressed in...
Renal antiporter ClC-5 regulates collagen I/IV through the {beta}-catenin pathway and lysosomal degradation
Life Science Alliance - New York
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April 26, 2024
Introduction Renal fibrosis is a common pathological process occurring as a consequence of chronic kidney injury, independently of the underlying disease aetiology (1). It is characterized by pathological deposition and accumulation of ECM in the...
Tate & Lyle enters into long-term agreement on the supply of raw sugar with Fiji Sugar Corporation Ltd
Tate & Lyle
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May 9, 2008
As announced earlier today by the Fiji Sugar Corporation Ltd, Tate Lyle has entered into a long-term agreement on the supply of raw sugar for preferential import into the European Union market. The contract for the supply of up to 300,000 tonnes...
Combining sophisticated fast FLIM, confocal microscopy, and STED nanoscopy for live-cell imaging of tunneling nanotubes
Life Science Alliance - New York
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April 22, 2024
Introduction The direct connection between distant cells via tunneling nanotubes (TNTs) is now well documented in many cell lines (Pinto et al, 2020; Roehlecke & Schmidt, 2020). The architecture of TNTs and the identification of their components...
Radware Launches EPIC-AI to Deliver New AI-Powered Intelligence and GenAI Capabilities Across its Security Solutions and Services
GlobeNewswire, Inc.
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July 31, 2024
MAHWAH, N.J., July 31, 2024 (GLOBE NEWSWIRE) -- Radware® (NASDAQ: RDWR), a leading provider of cyber security and application delivery solutions, today announced the launch of its proprietary Radware EPIC-AI™, which adds multiple layers of...
pADP-ribosylation regulates the cytoplasmic localization, cleavage, and pro-apoptotic function of HuR
Life Science Alliance - New York
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March 27, 2024
Introduction The RNA-binding protein (RBP) human antigen R (HuR) is ubiquitously expressed. It contains three highly conserved RNA-binding domains also known as RNA recognition motifs (RRMs; RRM1-3), and a hinge region between RRM2 and RRM3 that...
Genetic mutation of Cep76 results in male infertility due to abnormal sperm tail composition
Life Science Alliance - New York
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April 3, 2024
Introduction Cilia and their organelle cousins, flagella, play essential roles in many cell types. Notably, a single modified motile cilium (a flagellum) projects from male gametes and is essential for fertility in sexually reproducing animals...
Starvation-resistant cavefish reveal conserved mechanisms of starvation-induced hepatic lipotoxicity
Life Science Alliance - New York
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March 11, 2024
Introduction Starvation is a severe form of malnutrition that occurs when an individual’s intake of food is inadequate to meet their body’s energy requirements. Prolonged starvation can cause permanent organ damage, stunted growth in children, and...
Differential effects of translation inhibitors on Plasmodium berghei liver stage parasites
Life Science Alliance - New York
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April 4, 2024
Introduction Plasmodium parasite resistance to antimalarial drugs is a serious problem throughout endemic regions and underscores the need for new antimalarial drugs that work against novel drug targets (1). In addition to killing asexual blood...
Genetic ablation of Immt induces a lethal disruption of the MICOS complex
Life Science Alliance - New York
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March 11, 2024
Abstract The mitochondrial contact site and cristae organizing system (MICOS) is important for crista junction formation and for maintaining inner mitochondrial membrane architecture. A key component of the MICOS complex is MIC60, which has been...
CRL4DCAF1 ubiquitin ligase regulates PLK4 protein levels to prevent premature centriole duplication
Life Science Alliance - New York
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March 15, 2024
Introduction Centriole biogenesis has to be tightly controlled to prevent aberrant centrosome number, which can lead to chromosome missegregation and aneuploidy and has been associated with cancer (Nigg & Holland, 2018). Centriole duplication is...